Ramona, residing on her wealthy Spanish adoptive mother's rancho in California, falls in love with the Indian Alessandro. When Ramona is denied permission to marry Alessandro, the lovers elope, only to find a life of great hardship and unhappiness amidst the greed and injustice of the white landowners.

• American Mutoscope & Biograph
• Biograph Company
• Mary Pickford
• Henry B. Walthall
• Francis J. Grandon
• Kate Bruce
• W. Chrystie Miller
• Charles West
• Dorothy West
• Frank Opperman