UFC Fight Night 189: Rozenstruik vs. Sakai was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on June 5, 2021 UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A heavyweight bout between Jairzinho Rozenstruik and Augusto Sakai served as the event's headliner.

• Ultimate Fighting Championship
• Jairzinho Rozenstruik
• Augusto Sakai
• Marcin Tybura
• Walt Harris
• Roman Dolidze
• Laureano Staropoli
• Santiago Ponzinibbio
• Miguel Baeza